|
|
 |
Avitene
Instat
Ultrafoam |
Gelfoam
Spongostan
Surgifoam |
Thrombin |
Surgicel |
Bone Wax |
Agent
|
Alkylene Oxide Copolymers |
Microfibrillar Collagen |
Gelatin |
Thrombin |
Oxidized Regenerated
Cellulose |
Beeswax |
| Supplied |
Bars |
Sheets/powder |
Sheets/powder |
Powder / Solution |
Sheets |
Bars |
| Ingredients |
Water soluble
Synthetic copolymers |
Bovine Corium Collagen |
Animal Gelatin |
Bovine Thrombin |
Wood pulp |
Beeswax, Vaseline,
Isopropylpalmitate |
| Action |
Mechanical occlusion |
Platelet release stimulation |
Mechanical occlusion,
swells, Gel formation |
Activates Fibrin |
Mechanical occlusion
Swells, gel formation |
Mechanical occlusion |
| Remains at Site |
24 - 48 hours |
<12 weeks |
4 - 6 weeks |
minutes |
Variable |
Indefinitely |
| Advantages |
• Immediate hemostasis
• Ease of use
• Adheres to wet surfaces |
• Immediate hemostasis
• Binds to surfaces
• Does not swell |
• Binds to surfaces |
• Hemostasis in 2+ min
• Improves gelatin
sponge performance
|
• Bacteriostatic |
• Immediate hemostasis
• Ease of use |
Adverse Effects
|
• None known |
• Interferes with healing
• Allergic reactions
• Infection
• Adhesion formation
|
• Interferes with healing
• Cord compression
• Swelling
• Encapsulation of fluid
• Foreign body reactions
• Plasma leakage
• Nidus for infection
• Fever
|
• Allergic reactions
• Antibody formation
|
• Interferes with healing
• Cord compression
• Swelling
• Encapsulation of fluid
• Foreign body reactions
|
• Inhibits bone formation
• Allergic reactions
• Giant cell granulomas
• Cerebrospinal fluid leakage
• Nidus for infection
• Inflammation
• Pain
|
